www.AcademicAllergy.com

No evidence so far that COVID-19 was transmitted to humans from animals. Although this type of transmission is rare it was the case for SARS and MERS. Canine and feline coronaviruses, only infect animals and do not infect humans.

Coronaviral Life Cycle may be altered by interacting on the viral N protein. An excellent breakthrough for controlling all Corona virus infections published in one of the top impact journals on virology “Journal of Virology“.

Unless you have one of these diseases. Watch…

Asthma patients with sinusitis, polyps fare poorly after sinus surgery. https://www.mdedge.com/chestphysician/article/193324/asthma/asthma-patients-sinusitis-polyps-fare-poorly-after-sinus

Food Allergy Tests should only be done with the allergen that correlates with the clinical allergic reaction, thus a thorough investigation trying to establish link with the appropriate allergen must be done before ordering unnecessary tests.

There is no cause and effect connection between contrast media reactions and seafood allergy

Allergic to wheat? Here are the alternatives If you must avoid wheat, there are many tasteful alternatives. Read this article in Medical news

Optimize Skin Care Antihistamines Topical Corticosteroids (or calcineurin antagonists)  Dilute bleach soaks Eliminate triggers Skin hydration: Warm soaking followed by application of a moisturizer

managed our children’s anaphylactic food allergies, asthma, eczema, & seasonal allergies for 13 years. Excellent source for our patients https://milkallergymom.com

Approximately 70 percent of kids with likely IgE milk allergy can tolerate baked milk products,” she said. “We know it’s hard for parents to avoid milk, so don’t just assume your child can’t tolerate it.” When Miles was diagnosed, Kauffman didn’t know anyone else dealing with this concern, so she started a blog, Milk Allergy Mom,…

Keep molds away

Keep mites away

First thing is first, keep allergens away

First thing is first, keep allergens away

Food allergies are commonhttp://www.cnn.com/2011/HEALTH/06/20/food.allergies.pediatrics/index.html?iphoneemail

Tick like bugs are causing major allergic reactions in some people. Eradication of the bug does not seem to help since their body parts remain in the environment  and continue becoming nuisance.

A recent BJD article links early antibiotic exposure to risk for eczema. http://e2.ma/click/3sqfc/vi9soe/rnq2x

Allergy treatments abridged into a comprehensive capsule.

Pollens are just a masterpiece of art. Their names are difficult to pronounce but that’s how they are described among medical professionals.

http://www.mmsend55.com/link.cfm?r=45375272&sid=75914248&m=10244313&u=EA_ACAAI&j=27970800&s=http://college.acaai.org/members/Pages/ConsensusCommunicationonEarlyPeanutIntroductionandthePreventionofPeanutAllergyinHighRiskInfants.aspx

Cool showers with nondrying soap, avoiding oily creams which may block the skin pores helps. Calamine lotion is excellent for the itchy skin.

Maybe confused with hives. May even be triggered by sunlight through glass. Systemic symptoms sometimes seen.

The results of a New Zealand study found that babies who were regularly fed yogurt had significantly lower rates of allergies and eczema, Health Central reported. A total of 390 mothers in Auckland and Wellington Feeding Your Baby Yogurt Might Help Prevent This Serious Health Issue, Study Says – Romper https://apple.news/A_FMbr1zXQ9KIWMUP-NX5fA

A symptom of allergies and nasal congestion we commonly see in our office.

PMLE — Polymorphic Light Eruption, typically produces an itchy or burning rash within the first two hours after sun exposure

RORα regulates the expression of several genes important for Treg cell migration and function

I vividly recall the excitement on the faces of thousands of physicians attending the AAAAI meeting back in 1986 where for the first time the significance of IL5 was being introduced to the allergy arena. Now we are using Nucala: mepolizumab; anti-interleukin [IL]-5 on select patients. New biologicals are the key to success

Lung conditions causing a blood eosinophilia of greater than 1.5M/mL are severe eosinophilic asthma exacerbations, AFAD, EP, EGPA, and HES

Florida school drama was the main topic in the office today. Shannon Watts, Founder of Moms Demand Action for Gun Sense in America

Researchers discover receptor that protects against allergies, asthma – Wills-Karp and colleagues, including postdoctoral researcher Naina Gour, PhD, and assistant scientist Stephane Lajoie, PhD, who were first authors of the study, studied mice that were genetically engineered to lack dectin-1 were protected from allergic reactions. published online February 23 in Science Immunology

We encountered the most typical case of Progesterone hypersensitivity.

Patient seen today was carrying an Epipen for a previous anaphylactic episode of undetermined origin but had no records of baseline tryptase levels. All such patients should be screened for all forms of mast cell activation disorders.

Patient with known soy allergy claims drinking soy milk without problems but has a history of major allergic reaction to Tofu. It turns out pepsin degrades the beta-conglycinin in soy milk, but not in tofu. The difference in allergen stability determines outcome.

COX 2 inhibitors are the medication of choice in patients with ASA sensitivity. I don’t recall any incident of reaction to COX 2 inhibitors in patients with aspirin sensitivity. But a report of a patient who reacted to COX 2 inhibitor happened to be on low dose 100 mg aspirin prophylaxis for anti-platelet effect for…

After premedication protocol we start with ketorolac nasal spray and discharge the patient after 325 mg aspirin challenge.

Understanding food allergies –  https://knowridge.com/2018/02/understanding-food-allergies/

Low dose aspirin commonly used to reduce cardiovascular risk. We commonly encounter patients with ASA allergy. Aspirin desensitization is of great help for these patients.

Eosinophilia was the topic of the day in office. Remembering a conference where Dr Gleich quoted his recent publication. “A simple clinical test, namely inspection of the nail beds for evidence of splinter haemorrhages can alert the clinician to ongoing embolization. Any patient with marked eosinophilia who satisfies the criteria for HES, and splinter nail…

Allergic disease may be a camouflage for hyper eosinophilia in select patients. The risk of dissemination of strongyloides or other Helminthic infestations with glucocorticoid therapy is always in the back of our minds. Any patient with high Eos especially during remission of their allergies or ≥1500 eosinophils/microL at any given time should be evaluated properly.

The newer guidelines for Immunoglobulin therapy helped us take better care of Common Variable Immunodeficiency patients. Select patients especially with bronchiectasis may need prophylactic antibiotics. Bactrim, Amoxicillin or Azithromycin are commonly preferred. Patients with the most challenging bronchiectasis are the elderly who may coincidently have arrhythmias, need to be extra careful on those patients with…

Let’s not forget Cromolyn (Sodium Cromoglycate) Inhalation will prevent Aspirin Exacerbated Respiratory Disease.  ..and of course the exercise induced respiratory disease as well.  I was digging through the chart of a patient today, noticed my notes from the 90’s. Cromolyn, a drug for the hall of fame, still one of the best. 

Pain killer drug allergy tops the charts in frequency among drug hypersensitivity reactions we see in office. The allergy phenotypes are categorized into 4 groups. Diagnosis and management of each group is outlined in my new upcoming book.

Monoclonal antibodies are often life saving. Desensitization with 12-bags protocol, similar to antibiotic protocols are commonly used. Rituximab allergy is one such example.

The drug allergy case today. Quinolone antibiotics have cross reactivities among their own groups with similar side chains. We don’t advise prescribing another quinolone before a negative drug provocation test in patients with no other alternatives. There are numerous cases of patients with Ciprofloxacine hypersensitivity who reacts to other quinolones, Fluoroquinolones, Levofloxacine, Moxifloxacine, Ofloxacine.

Protocols for desensitizations to chemotherapy drugs has been established. Most common applications are oxaliplatin, carboplatin, paclitaxel, docetaxel, cetuximab and rituximab

Fear of doctors. This is the encounter with my patient today. Now…where is he?

Oral Immunoterapy with food allergen doses usually start at less than 1 mg and increase to several milligrams. After the initial escalation, buildup stage the target dose reached and treated for up to 5 years with a peanut OIT maintenance dose of up to 4 g peanut protein per day for sustained unresponsiveness.

Currently there is a shift toward earlier introduction of allergenic foods to infants, as the updated guidelines specifically recommends.

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